An interesting article in The Huffington Post attempts to outline Romney's strategy to obtain the 2012 GOP nomination.
Romney's goal is to win New Hampshire and Nevada. Both states are good bets for Romney considering how they voted for him last time. Romney narrowly lost to McCain in NH, and then won Nevada. Then its on to Michigan and Florida. Another good bet considering 2008 when he won Michigan and narrowly lost to McCain in Florida that year. Iowa and South Carolina are not part of the plan. Romney will make a token effort in both states but not a major investment. Both Iowa and South Carolina are dominated by religious evangelicals who will much more like vote for another evangelical.
Also, an interesting change in the GOP process of winning delegates will likely help Romney. In the past, states used to have an "all-or-nothing" victory where the winner of the state got all of the state's delegates. Now, however, delegates will be awarded based on the percentage of the votes he gains in the states. This will help well-known and well-funded candidates like Romney tremendously.
So there you have it. A pretty good rundown of the 2012 Romney strategy. Sounds like a good bet to me.